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Read the latest reports, white papers, and case studies about how LynxCare is transforming RWE

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Poster | Real-World Insights on Pan-Cancer Immune Checkpoint Inhibitor Treatment: Initial Findings of a Belgian Multicenter Study
Publication
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To bridge the gap between clinical trial patients and real-world populations, we conducted a comprehensive study in Belgium to characterize cancer patients treated with immune checkpoint inhibitors (ICIs), which have demonstrated survival advantages in various cancer types.
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Poster | Building Federated Data Networks with Common Data Models to Generate Insights through Real-World Evidence Observational Studies in Oncology
Publication
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Accessing and standardizing raw clinical data across multiple hospitals presents a challenge in Oncology. However, it is crucial to use real-world data sources such as electronic health records (EHR) to leverage untapped information. We are building a federated data network to facilitate GDPR-compliant data exchange of large datasets, with hospitals as owners. This network, governed by a common data model (CDM), is aimed at fostering multicenter, observational, real-world evidence (RWE) studies in Oncology, with breast cancer, lung cancer, and immunotherapy as therapeutic areas of focus.
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Use Case | Using AI and NLP on EHRs of Heart Failure patients to examine the impact of estimated glomerular filtration rate trend on mortality
Case Study
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This study aimed to investigate the prevalence of impaired renal function at the time of Heart Failure diagnosis and its correlation with short and long-term outcomes in a real-world cohort of Heart Failure patients.
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Abstract | Automatic data processing to identify EGFR mutations in pathology reports of patients with non-small cell lung cancer (NSCLC)
Publication
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NLP algorithms allow rapid data extraction from pathology reports, thereby offering a time-efficient and cost-effective alternative to manual data processing. In turn, this approach enables rapid insight in current biomarker testing rates and prevalence of (actionable) mutations.
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Publication | Detection of ATTR-CM by automated data extraction from EHRs | ESC Heart Failure
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Information held in Electronic Health Records (EHRs) hold a significant opportunity to provide physicians and researchers with better and more insights to improve disease management and treatment.
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Abstract | Automated retrospective data extraction from EHRs using NLP creating an OMOP-CDM database | OHDSI
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The study aimed to analyze individuals with ATTR-CM in a real-world heart failure patient population using a federated OMOP-CDM database generated from data of electronic health records.
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Use Case | Unlocking RWE about Immune Checkpoint Inhibitor Treatment in Diverse Cancer Types
Case Study
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RWE is becoming a valuable addition to randomized controlled clinical trials to better understand the mechanisms and outcomes of cancer treatments. However, most RWD is locked in a non-uniform patient reporting system by hospitals and healthcare professionals. Download our use case in immuno-oncology by completing the form and read how artificial intelligence can help unlock real-world evidence in immunotherapy.
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Use Cases | Heart Failure
Case Study
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Discover how combining clinical expertise, real-world data and technology can save lives of heart failure patients.
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Publication | Cardio–renal–metabolic syndrome | ESC Heart Failure
Publication
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An example of the power of real-world data, technology and collaboration to transform patient care. The study aimed to shed light on patient eligibility for SGLT2 inhibitors as a therapy for heart failure patients, providing valuable information for clinicians and researchers.
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”We're an active contributor to establishing the pan-European Health Data Evidence Network (EHDEN) and are eager to contribute to building the European Health Data Space to make a more inclusive European healthcare system for all patients.”

Georges De Feu
Co-founder & CEO, LynxCare